Ananas: Controindicazioni e Bibliografia

Ultima modifica 12.02.2020

A cura della Dott.ssa Rita Fabbri

Controindicazioni, avvertenze speciali ed opportune precauzioni d'uso, effetti indesiderati

Per l'Ananas, non abbiamo studi clinici condotti su donne in gravidanza ed in allattamento;  in questi casi è quindi opportuno informare il medico prima di assumere prodotti che la contengono. I preparati a base di Ananas sono controindicati nei soggetti con ulcera peptica e nei pazienti in terapia anticoagulante (59). La Bromelina può aumentare l'assorbimento di tetracicline e amoxicillina:

  • In uno studio in doppio cieco effettuato su 127 pazienti, la Bromelina ha significativamente aumentato i livelli sierici di amoxicillina rispetto al gruppo di controllo trattato con amoxicillina e placebo. Inoltre, nel gruppo a Bromelina si sono riscontrati livelli tissutali di amoxicillina significativamente maggiori (47).

Risultati similari sia per l'amoxicillina che per le tetracicline, sono stati riportati in uno studio controllato con placebo effettuato su 54 pazienti trattati con Bromelina (46).
Sebbene non siano noti effetti collaterali significativi, potrebbero verificarsi reazioni allergiche in individui sensibili oppure esposti per ragioni professionali (60-61). Altre possibili reazioni, anche se non confermate, comprendono nausea, vomito, diarrea, metrorragia e menorragia (62).


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  44.  Maurer HR, et al: Bromelain induces the differentiation of leukemic cells in vitro: An explanation for its cytostatic effects? Planta Medica 54, 377-381, 1988.
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  61.  Baur X and Fruhman G: Allergic reaction, including asthma, to the pineapple protease Bromelain following occupational exposure. Clin Allergy 9, 443-450, 1979.
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